Sound Medicine -- February 2, 2002

Barbara Lewis and Dr. Kathy Miller talk to physicians and researchers about:

Baby heart defects
The hope of heart regeneration
Women and heart attacks
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Baby heart defects

Expectant parents are always a little anxious during a pre-natal ultrasound. Usually, the doctor can assure them everything's fine by pointing out the head, the feet, maybe even a fist while they listen to the reassuring thumpity-thumpity of the tiny beating heart. Unfortunately, not all those fetal heart-beats reassure doctors.

Dr. Kathy Miller and Barbara Lewis meet with Dr. Donald Girod, professor of pediatrics, and director of Indiana University's pediatric cardiology division. He relates common problems, such as a hole in the heart or blue baby syndrome. Dr. Girod describes surgical procedures for repairing baby hearts, sometimes in utero operations, and prognoses for these children.

Resources
The Congenital Heart Information Network information provides reliable support and resources for families of children with congenital heart defects.
The Riley Hospital for Children has offered pediatric cardiology services since 1950. Read here about common procedures.
Want to know what happens in the pediatric cardiology section of a hospital? Here's an interesting outline from the University of Chicago Children's Hospital.

The hope of heart regeneration

Recently released studies featured in the New England Journal of Medicine (NEJM) describe signs of regenerated cells among heart transplant patients. If true, these findings could mean renewed hope for people suffering from irreparable heart damage. The findings are preliminary, however.

Dr. Loren Field joins us to discuss these studies. He explains that although they provide excellent data for cardiac research, they are small steps toward full-fledged human heart regeneration. Dr. Field is a professor of medicine, physiology and biophysics at Indiana University. His cardiac research includes myocardial regeneration, the cardiomyocyte cell cycle, and cardiac grafts.

Professor of Medicine and Pediatrics, Dr. Edward Srour explains the role of bone marrow stem cells in heart cell regeneration. Dr. Srour talks about bone marrow and its role in helping broken hearts mend. In a recent study, patients' ailing hearts were injected with stem cells from their own bone marrow, in hopes that the as yet undeveloped cells would grow into heart cells, replacing those lost to damage or disease. The findings were positive. Dr. Srour describes the mechanics of the procedure and how the study's results fit into the big picture of heart cell regeneration.

Resources
This brief article presents an overview of the study published in the January 3, 2002 issue of the NEJM.
Read about organ regeneration research underway at the Howard Hughes Medical Institute (HHMI), in Dr. Mark Keating's laboratory.
In June of 2001, a team of scientists published evidence that human heart muscle cells regenerate after a heart attack, again in the NEJM.

Women and hearts attacks

Heart disease accounts for the highest number of deaths among women, averaging about half a million a year. But with so much publicity focused on the serious health risks more unique to women, such as cervical, ovarian and breast cancers, heart problems in women tend to be overlooked. A recent study, however, indicated more women die of heart complications in the hospital than men, perhaps due to slower diagnoses.

We talk with Dr. Elisabeth von der Lohe, who explains that because women have different heart attack warning signs, women experiencing cardiac arrest may have a delay in care.

Von der Lohe is medical director of Indiana University Hospital's Women's Heart Clinic and clinical associate professor of medicine specializing in heart related issues particular to women. She is an interventional cardiologist.

Resources
Find out how women's hearts physiologically differ from men's at the Women's Heart Institute.
The Women's Heart Foundation is an excellent Web site, with links to doctor-recommended diets, exercise plans, guides to medicine and surgery -- even on-line tests to measure heart risks.
Read more about women's health at the National Women's Health Information Center.

 

 
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This week's Medical Mystery — a winter-time affliction
One name for it is xerosis. Another term is asteatosis. It often strikes in the wintertime, and it particularly affects older folks. It can be merely annoying, or cause itching, even pain. Unfortunately, staying at home to avoid contracting this condition won't work.

What is this mysterious condition?


Health Quiz — Watch those eyes
If you are over 60 years old, or if you're an African American over 40 years old, there's a vision problem you're susceptible to, and need to be examined for. Which of the following three eye conditions are we talking about?

A. Near-sightedness
B. Detached retina
C. Glaucoma

What's the truth?


Weekly Notebook: Warning signs of heart attack

Uncomfortable pressure, fullness, squeezing or pain in the center of the chest that lasts for more than a few minutes, or goes away and comes back.
• Pain that spreads to the shoulders neck or arms.
• Chest discomfort along with light-headedness, fainting, sweating, nausea, or shortness of breath.

Heart attack warning signs more common in women

• Unusual chest pain, stomach or abdominal pain.
• Nausea or dizziness, without chest pain
• Shortness of breath with difficulty breathing
• Unexplained anxiety, weakness or extreme fatigue.
• Palpitations, cold sweat or paleness

Source: National Women's Health Information Center