Indiana University

Aspirin resistance or 'pseudo-resistance?'

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Air date: March 10, 2013

Host: Steve Bogdewic, PhD

Men's & Women's Health Research Medical Edcuation
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Interview: Tilo Grosser, M.D., research assistant professor of pharmacology, University of Pennsylvania, Perelman School of Medicine.



Around one-fifth of Americans take some form of low dose aspirin daily for its heart healthy benefits and it’s believed that up to one-third of these patients are aspirin resistant. Tilo Grosser, M.D., is the author of a new study that concludes many diagnoses of aspirin resistance are actually false, a condition known as pseudo-resistance. According to Dr. Grosser, many low-dose aspirin tablets are coated to prevent damage to the stomach. However. Dr. Grosser’s study finds that this coating may actually cause a false diagnosis of aspirin resistance. The study of 400 patients found that less than 0.25 percent of the subjects were actually aspirin resistant.

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